Tizanidine hydrochloride
Cat. No.：YN321418
CAS No. ：64461-82-1
| 产品名称: | Tizanidine hydrochloride |
| CAS No.: | 64461-82-1 |
| Chemical Name: | 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine, monohydrochloride |
| Synonyms: | 盐酸替扎尼定 |
| 分子量: | 290.17 |
| 分子式: | C₉H₉Cl₂N₅S |
| SMILES: | ClC1=C(NC2=NCCN2)C3=NSN=C3C=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tizanidine盐酸盐是α2-肾上腺素受体激动剂，能抑制神经递质从CNS去甲肾上腺素激活的神经元中释放。 |
| IC50和靶点: | |
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Sakitani, K.The effects of centrally acting muscle relaxants on the intrathecal noradrenaline-induced facilitation of the flexor reflex mediated by group II afferent fibers in ratsJpn. J. Pharmacol.63(3),369-376(1993)
Sayers, A.C., Bürki, H.R., and Eichenberger, E.The pharmacology of 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole (DS 103-282), a novel myotonolytic agentArzneimittelforschung30(5),793-803(1980)
Sklerov, J.H., Cox, D.E., Moore, K.A., et al.Tizanidine distribution in a postmortem caseJ. Anal. Toxicol.30(5),331-334(2006)
