(R)-Terazosin
Cat. No.：YN321466
| 产品名称: | (R)-Terazosin |
| CAS No.: | 109351-34-0 |
| Chemical Name: | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[[(2R)-tetrahydro-2-furanyl]carbonyl]- piperazine; [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(2R)-tetrahydro-2-furanyl]methanone; |
| Synonyms: | (R)-特拉唑嗪 |
| 分子量: | 387.43 |
| 分子式: | C₁₉H₂₅N₅O₄ |
| SMILES: | O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)[C@@H]4OCCC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-Terazosin 是 Terazosin 的活性 R 型对应体, 是一种有效的 α1-肾上腺素受体拮抗剂，对α1a，α1b和α1d-肾上腺素受体的Ki值分别为 6.51 nM，1.01 nM 和 1.97 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Patterson, S.E., et al.: J. Chromatog., 311, 206 (1984), Fort, F.L., et al.: Drug Chem. Toxicol., 7, 435 (1984), Lepor, H., et al.: J. Urol., 148, 1467 (1992), Lin, H. et al.: Nat. Methods., 10, 140 (2013)
