Xylometazoline hydrochloride
Cat. No.：YN321513
| 产品名称: | Xylometazoline hydrochloride |
| CAS No.: | 1218-35-5 |
| Chemical Name: | 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-1H-imidazole, monohydrochloride |
| Synonyms: | 盐酸赛洛唑啉 |
| 分子量: | 280.84 |
| 分子式: | C₁₆H₂₅ClN₂ |
| SMILES: | CC1=C(CC2=NCCN2)C(C)=CC(C(C)(C)C)=C1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Xylometazoline 盐酸盐是 α- 肾上腺素受体激动剂，为鼻血管收缩药。 |
| IC50和靶点: | [{name:"Alpha-1A adrenergic receptor:0.05 μM (Ki)"},{name: "Alpha-1B adrenergic receptor:0.30 μM (Ki)"},{name: "Alpha-1D adrenergic receptor:0.15 μM (Ki)"},{name: "Alpha-2A adrenergic receptor:0.88 μM (Ki)"},{name: "Alpha-2B adrenergic receptor:1.7 μM (Ki)"},{name: "Alpha-2C adrenergic receptor:0.19 μM (Ki)"}] |
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Haenisch, B., Waltstab, J., Herberhold, S., et al.Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazolineFundam. Clin. Pharmacol.24(6),729-739(2010)
Law, H., Dukat, M., Teitler, M., et al.Benzylimidazolines as h5-HT1B/1D serotonin receptor ligands: A structure-affinity investigationJ. Med. Chem.41(13),2243-2251(1998)
Jackson, R.T., and Birnbaum, J.E.A comparison of a synthetic prostaglandin and xylometazoline hydrochloride as nasal decongestantsOtolaryngol. Head Neck Surg.90(5),595-597(1982)
