Brimonidine
Cat. No.：YN321551
CAS No. ：59803-98-4
| 产品名称: | Brimonidine |
| CAS No.: | 59803-98-4 |
| Chemical Name: | 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine |
| Synonyms: | UK 14304; AGN190342 |
| 分子量: | 292.13 |
| 分子式: | C₁₁H₁₀BrN₅ |
| SMILES: | BrC1=C2N=CC=NC2=CC=C1NC3=NCCN3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Brimonidine (UK 14304) 是完全的α2肾上腺素受体激动剂。 |
| IC50和靶点: | |
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Munk, S.A., Harcourt, D.A., Arasasingham, P.N., et al.Synthesis and evaluation of 2-(arylamino)imidazoles as α2-adrenergic agonistsJ. Med. Chem.40(1),18-23(1997)
Sawada, K., Hiraoka, M., and Ohguro, H.Effect of antiglaucoma medicine on intraocular pressure in DBA/2J miceOphthalmic Res.55(4),205-211(2016)
Lee, D., Kim, K.Y., Noh, Y.H., et al.Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor A in ischemic retinal injuryPLoS One7(10),e47098(2012)
