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Tamsulosin hydrochloride

Cat. No.:YN321554

  • CAS No. :106463-17-6

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    • 产品名称: Tamsulosin hydrochloride
      CAS No.: 106463-17-6
      Chemical Name: 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-benzenesulfonamide, monohydrochloride
      Synonyms:盐酸坦索罗辛; (R)-(-)-YM12617; LY253351
      分子量:444.97
      分子式:C₂₀H₂₉ClN₂O₅S
      SMILES:O=S(C1=CC(C[C@H](NCCOC2=CC=CC=C2OCC)C)=CC=C1OC)(N)=O.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tamsulosin盐酸盐(R-(-)-YM12617;LY253351)是α1受体选择性拮抗剂。
      IC50和靶点:
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    • Honda, K., Takenaka, T., Miyata-Osawa, A., et al.Studies on YM-12617: A selective and potent antagonist of postsynaptic α1-adrenoceptorsNaunyn Schmiedebergs Arch. Pharmacol.328(3),264-272(1985)

      Ratnasooriya, W.D., and Wadsworth, R.M.Tamsulosin, a selective alpha 1-adrenoceptor antagonist, inhibits fertility of male ratsAndrologia26(2),107-110(1994)

      Sudoh, K., Tanaka, H., Inagaki, O., et al.Effect of tamsulosin, a novel alpha 1-adrenoceptor antagonist, on urethral pressure profile in anaesthetized dogsJ. Auton. Pharmacol.16(3),147-154(1996)

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