Lofexidine hydrochloride
Cat. No.：YN321602
CAS No. ：21498-08-8
| 产品名称: | Lofexidine hydrochloride |
| CAS No.: | 21498-08-8 |
| Chemical Name: | 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole, monohydrochloride |
| Synonyms: | 盐酸洛非西定; Baq-168; MDL-14042 |
| 分子量: | 295.59 |
| 分子式: | C₁₁H₁₃Cl₃N₂O |
| SMILES: | CC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lofexidine (hydrochloride) 是选择性的、α2 受体激动剂，常用于缓解海洛因和其他阿片类戒断的躯体症状。 |
| IC50和靶点: | |
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Bennett, D.A., and Lal, H.Discriminative stimuli produced by clonidine: An investigation of the possible relationship to adrenoceptor stimulation and hypotensionJ. Pharmacol. Exp. Ther.223(3),642-648(1982)
Ling, W., Mooney, L., Zhao, M., et al.Selective review and commentary on emerging pharmacotherapies for opioid addictionSubst. Abuse Rehabil.2,181-188(2011)
Gerra, G., Zaimovic, A., Giusti, F., et al.Lofexidine versus clonidine in rapid opiate detoxificationJ. Subst. Abuse Treat.21(1),11-17(2001)
