Oxprenolol hydrochloride
Cat. No.：YN321659
CAS No. ：6452-73-9
| 产品名称: | Oxprenolol hydrochloride |
| CAS No.: | 6452-73-9 |
| Chemical Name: | 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-2-propanol, monohydrochloride |
| Synonyms: | Ba 39089 |
| 分子量: | 301.81 |
| 分子式: | C₁₅H₂₄ClNO₃ |
| SMILES: | OC(COC1=CC=CC=C1OCC=C)CNC(C)C.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oxprenolol hydrochloride (Ba 39089) 是一种口服有效的 β-肾上腺素受体 (β-AR) 拮抗剂，Ki为 7.10 nM。 |
| IC50和靶点: | [{name:"β-adrenoceptor:7.1 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Nagatomo, T., Sasaki, M., Tsuchihashi, H., et al.Binding characteristics of 3H-dihydroalprenolol to β-adrenoceptors of rat heart treated with neuraminidaseJpn. J. Pharmacol.33(4),851-857(1983)
Abrahamsson, T.The β1- and β2-adrenoceptor stimulatory effects of alprenolol, oxprenolol and pindolol: A study in the isolated right atrium and uterus of the ratBr. J. Pharmac.87(4),657-664(1986)
Moretti-Rojas, I., Ezrailson, E.G., Birnbaumer, L., et al.Serotonergic and adrenergic regulation of skeletal muscle metabolism in the rat. II. The use of [125I]iodolysergic acid diethylamide and [125I]iodopindolol as probes of sarcolemmal receptor function and specificityJ. Biol. Chem.258(20),12499-12508(1983)
Langlois, M., Brémont, B., Rousselle, D., et al.Structural analysis by the comparative molecular field analysis method of the affinity of β-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptorsEur. J. Pharmacol.244(1),77-87(1993)
Russo, M.E., and Covinsky, J.O.Oxprenolol hydrochloride: Pharmacology, pharmacokinetics, adverse effects and clinical efficacyPharmacotherapy3(2),68-81(1983)
