(R)-(+)-Atenolol
Cat. No.：YN321693
| 产品名称: | (R)-(+)-Atenolol |
| CAS No.: | 56715-13-0 |
| Chemical Name: | 4-[(2R)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetamide |
| Synonyms: | |
| 分子量: | 266.34 |
| 分子式: | C₁₄H₂₂N₂O₃ |
| SMILES: | O=C(N)CC1=CC=C(OC[C@H](O)CNC(C)C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-(+)-Atenolol 是活性较低的 (R,S)-atenolol 的对映体。(R,S)-atenolol 是 β-肾上腺素能受体拮抗剂。 |
| IC50和靶点: | |
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Stoschitzky, K., Egginger, G., Zernig, G., et al.Stereoselective features of (R)- and (S)-atenolol: Clinical pharmacological, pharmacokinetic, and radioligand binding studiesChirality5(1),15-19(1993)
Richer, C., Boissier, J.R., and Giudicelli, J.F.Chronic atenolol treatment and hypertension development in spontaneously hypertensive ratsEur. J. Pharmacol.47(4),393-400(1978)
Pearson, A.A., Gaffney, T.E., Walle, T., et al.A stereoselective central hypotensive action of atenololJ. Pharmacol. Exp. Ther.250(3),759-763(1989)
