Yohimbine Hydrochloride
Cat. No.：YN321708
| 产品名称: | Yohimbine Hydrochloride |
| CAS No.: | 65-19-0 |
| Chemical Name: | 17α-hydroxy-yohimban-16α-carboxylic acid, methyl ester, monohydrochloride |
| Synonyms: | Antagonil |
| 分子量: | 390.90 |
| 分子式: | C₂₁H₂₇ClN₂O₃ |
| SMILES: | [H][C@]12C(NC3=C4C=CC=C3)=C4CCN1C[C@@]5(CC[C@H](O)[C@H](C(OC)=O)[C@]5(C2)[H])[H].[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Yohimbine Hydrochloride 是 α-2肾上腺素能受体抑制剂，阻断突触前或突触后的 α-2肾上腺素能受体，引起去甲肾上腺素和多巴胺的释放。 |
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Millan, M.J., Newman-Tancredi, A., Audinot, V., et al.Agonist and antagonist actions of yohimbine as compared to fluparoxan at α2-adrenergic receptors (AR)s, serotonin (5-HT)1A, 5-HT1B, 5-HT1D and dopamine D2 and D3 receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive statesSynapse35(2),79-95(2000)
Schwartz, D.D., and Clark, T.P.Selectivity of atipamezole, yohimbine and tolazoline for alpha-2 adrenergic receptor subtypes: Implications for clinical reversal of alpha-2 adrenergic receptor mediated sedation in sheepJ. Vet. Pharmacol. Ther.21(5),342-347(1998)
