Isoferulic acid
Cat. No.：YN321733
| 产品名称: | Isoferulic acid |
| CAS No.: | 537-73-5 |
| Chemical Name: | 3-(3-hydroxy-4-methoxyphenyl)-2-propenoic acid |
| Synonyms: | 3-Hydroxy-4-methoxycinnamic acid |
| 分子量: | 194.18 |
| 分子式: | C₁₀H₁₀O₄ |
| SMILES: | O=C(O)/C=C/C1=CC=C(OC)C(O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) 是具有抗糖尿病活性的肉桂酸衍生物。Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) 结合并激活 α1-肾上腺素能受体 (IC50=1.4 μM)，增强 β-内啡肽的分泌 (EC50=52.2 nM) 并增加体外葡萄糖的使用。Isoferulic acid 还具有抗流感病毒的活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Liu, I.-M., Tsai, C.-C., Lai, T.-Y., et al.Stimulatory effect of isoferulic acid on α1A-adrenoceptor to increase glucose uptake into cultured myoblast C2C12 cell of miceAuton. Neurosci.88(3),175-180(2001)
Liu, I.-M., Chen, W.-C., and Cheng, J.-T.Mediation of β-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic ratsJ. Pharmacol. Exp. Ther.307(3),1196-1204(2003)
Liu, I.-M., Hsu, F.-L., Chen, C.-F., et al.Antihyperglycemic action of isoferulic acid in streptozotocin-induced diabetic ratsBr. J. Pharmacol.129(4),631-636(2000)
Adisakwattana, S., Chantarasinlapin, P., Thammarat, H., et al.A series of cinnamic acid derivatives and their inhibitory activity on intestinal alpha-glucosidaseJ. Enzyme Inhib. Med. Chem.24(5),1194-1200(2009)
