Glaucine
Cat. No.：YN321761
| 产品名称: | Glaucine |
| CAS No.: | 475-81-0 |
| Chemical Name: | (6aS)-5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline |
| Synonyms: | O,O-Dimethylisoboldine; S-(+) |
| 分子量: | 355.43 |
| 分子式: | C₂₁H₂₅NO₄ |
| SMILES: | CN1CCC2=CC(OC)=C(OC)C3=C2[C@]1([H])CC4=CC(OC)=C(OC)C=C34 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Glaucine (O,O-Dimethylisoboldine) 是一种从Glaucium flavumCrantz 中分离的生物碱，具有镇咳，支气管扩张和抗炎作用。 Glaucine 是一种选择性的，具有口服活性的磷酸二酯酶 4 (PDE4) 抑制剂，在人支气管和多形核白细胞中的Ki为 3.4 µM。Glaucine 还是一种非选择性的 α-肾上腺素受体 (α-adrenoceptor) 拮抗剂，一种Ca2+进入阻滞剂以及弱多巴胺D1和D2受体拮抗剂。Glaucine 具有抗氧化和抗病毒活性。 |
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Ujváry, I.Psychoactive natural products: Overview of recent developmentsAnn. Ist. Super. Sanità50(1),(2014)
Geppert, B., Wachowiak, R., and Żaba, C.Glaucine as a non-declared active component of "legal highs"Problems of Forensic Sciences84,401-408(2010)
