Tulobuterol hydrochloride
Cat. No.：YN322105
| 产品名称: | Tulobuterol hydrochloride |
| CAS No.: | 56776-01-3 |
| Chemical Name: | 2-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-benzenemethanol, monohydrochloride |
| Synonyms: | C-78 |
| 分子量: | 264.19 |
| 分子式: | C₁₂H₁₉Cl₂NO |
| SMILES: | CC(C)(NCC(O)C1=CC=CC=C1Cl)C.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tulobuterol hydrochloride (C-78) 是一种长效的 β2肾上腺素受体 (β2-adrenoceptor) 激动剂，可减少慢性阻塞性肺疾病和支气管哮喘的发作频率。Tulobuterol hydrochloride 也是一种拟交感神经药，用作透皮贴剂，可增加正常的横膈膜肌肉力量。Tulobuterol hydrochloride 抑制鼻病毒 (rhinovirus) 复制并调节气道炎症。 |
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IJzerman, A.P., Bultsma, T., and Timmerman, H.Quantitative evaluation of the β2-adrenoceptor intrinsic activity of N-tert-butylphenylethanolaminesJ. Med. Chem.29(4),549-554(1986)
Fu, L., Guan, J., Zhang, Y., et al.Tulobuterol patch alleviates allergic asthmic inflammation by blockade of Syk and NF-κB activation in miceOncotarget9(15),12154-12163(2018)
Yamaya, M., Nishimura, H., Nadine, L., et al.Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cellsPhysiol. Rep.1(3),e00041(2013)
