Aftin-4
Cat. No.：YN380043
CAS No. ：866893-90-5
| 产品名称: | Aftin-4 |
| CAS No.: | 866893-90-5 |
| Chemical Name: | 2R-[[9-(1-methylethyl)-6-[methyl(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Synonyms: | Aftin4,Aftin 4 |
| 分子量: | 368.48 |
| 分子式: | C₂₀H₂₈N₆O |
| SMILES: | CC[C@@H](NC1=NC(N(C)CC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1)CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aftin-4 是 β-淀粉样蛋白42(Aβ42) 的诱导剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Hochard, A., Oumata, N., Bettayeb, K., et al.Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: Toward a chemical model of Alzheimer's disease?J. Alzheim. Dis.35(1),107-120(2013)
Meunier, J., Borjini, N., Gillis, C.N., et al.Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivativeJ. Alzheim. Dis.44(2),507-524(2015)
