PBD-150
Cat. No.:YN380057
产品名称: | PBD-150 |
CAS No.: | 790663-33-1 |
Chemical Name: | N-(3,4-dimethoxyphenyl)-N′-[3-(1H-imidazol-1-yl)propyl]-thiourea |
Synonyms: | PBD 150;PBD150 |
分子量: | 320.41 |
分子式: | C₁₅H₂₀N₄O₂S |
SMILES: | S=C(NCCCN1C=CN=C1)NC2=CC=C(OC)C(OC)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PBD-150 是人谷氨酰胺酰基环化酶(hQC) Y115E-Y117E变体的抑制剂,其Ki值为490 nM。 |
IC50和靶点: | |
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Buchholz, M., Heiser, U., Schilling, S., et al.The first potent inhibitors for human glutaminyl cyclase: Synthesis and structure-activity relationshipJ. Med. Chem.49(2),664-677(2006)