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Ginsenoside Rg2

Cat. No.:YN380231

  • CAS No. :52286-74-5

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    • 生物活性
    • 参考文献
    • 产品名称: Ginsenoside Rg2
      CAS No.: 52286-74-5
      Chemical Name: (6α)-3β,12β,20-trihydroxydammar-24-en-6-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
      Synonyms:人参皂苷 Rg2; Chikusetsusaponin I; Panaxoside Rg2; Prosapogenin C2
      分子量:785.01
      分子式:C₄₂H₇₂O₁₃
      SMILES:C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(C[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]4O)([H])[C@@H]4O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)[C@@]2([H])C3(C)C)[C@]6([C@@]1([H])[C@]([C@@](C)(O)CC/C=C(C)/C)([H])CC6)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Ginsenoside Rg2 是人参的主要活性成分之一。Ginsenoside Rg2 是一种NF-κB抑制剂。 Ginsenoside Rg2 还降低Aβ1-42积聚。
      IC50和靶点:
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    • Liang, Y., and Zhao, S.Progress in understanding of ginsenoside biosynthesisPlant Biol. (Stuttg)10(4),415-421(2008)

      Chen, C.F., Chiou, W.F., and Zhang, J.T.Comparison of the pharmacological effects of Panax ginseng and Panax quinquefoliumActa Pharmacol. Sin.29(9),1103-1108(2008)

      Zhang, G., Liu, A., Zhou, Y., et al.Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementiaJ. Ethnopharmacol.115(3),441-448(2008)

      Cho, Y.S., Kim, C.H., Ha, T.S., et al.Ginsenoside Rg2 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cellKorean J. Physiol. Pharmacol.17(2),133-137(2013)

      Yuan, H.D., Kim, D.Y., Quan, H.Y., et al.Ginsenoside Rg2 induces orphan nuclear receptor SHP gene expression and inactivates GSK3β via AMP-activated protein kinase to inhibit hepatic glucose production in HepG2 cellsChem. Biol. Interact.195(1),35-42(2012)

      Ha, S.E., Shin, D.H., Kim, H.D., et al.Effects of ginsenoside Rg2 on the ultraviolet B-induced DNA damage responses in HaCaT cellsNaunyn Schmiedebergs Arch. Pharmacol.382(1),89-101(2010)

      Kim, I.W., Cha, K.M., Wee, J.J., et al.A new validated analytical method for the quality control of red ginseng productsJ. Ginseng Res.37(4),475-482(2013)

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