ZD 7155(hydrochloride)
Cat. No.:YN320220
CAS No. :146709-78-6
产品名称: | ZD 7155(hydrochloride) |
CAS No.: | 146709-78-6 |
Chemical Name: | 5,7-diethyl-3,4-dihydro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,6-naphthyridin-2(1H)-one, monohydrochloride |
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分子量: | 474.99 |
分子式: | C₂₆H₂₇ClN₆O |
SMILES: | O=C1CCC2=C(C=C(CC)N=C2CC)N1CC(C=C3)=CC=C3C4=CC=CC=C4C5=NN=NN5.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ZD 7155 hydrochloride是血管紧张素II受体1型 (AT1 receptor) 拮抗剂。 |
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Zhang, H., Unal, H., Gati, C., et al.Structure of the Angiotensin receptor revealed by serial femtosecond crystallographyCell161(4),833-844(2015)
Junggren, I.L., Zhao, X., Sun, X., et al.Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the ratJ. Pharm. Pharmacol.48(8),829-833(1996)
Maxfield, E.K., Love, A., Cotter, M.A., et al.Nerve function and regeneration in diabetic rats: Effects of ZD-7155, an AT1 receptor antagonistAm. J. Physiol.269(3 Pt 1),E530-537(1995)
Wang, F., Xia, Z.-F., Chen, X.-L., et al.Angiotensin II type-1 receptor antagonist attenuates LPS-induced acute lung injuryCytokine48(3),246-253(2009)