Azilsartan D5
Cat. No.：YN320932
| 产品名称: | Azilsartan D5 |
| CAS No.: | 1346599-45-8 |
| Chemical Name: | 2-(ethoxy-d5)-1-((2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid |
| Synonyms: | TAK-536 D5 |
| 分子量: | 461.48 |
| 分子式: | C₂₅H₁₅D₅N₄O₅ |
| SMILES: | OC(C1=CC=CC2=C1N(C(OC(C([2H])([2H])[2H])([2H])[2H])=N2)CC(C=C3)=CC=C3C4=CC=CC=C4C5=NC(ON5)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Azilsartan D5 (TAK-536 D5) 是 Azilsartan (TAK-536) 的氘代物。 |
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Kohara, Y., Kubo, K., Imamiya, E., et al.Synthesis and angiotensin II receptor antagonistic activities of benzimidazole derivatives bearing acidic heterocycles as novel tetrazole bioisosteresJ. Med. Chem.39(26),5228-5235(1996)
Ojima, M., Igata, H., Tanaka, M., et al.In vitro antagonistic properties of a new angiotensin type 1 receptor blocker, azilsartan, in receptor binding and function studiesJ. Pharmacol. Exp. Ther.336(3),801-808(2011)
Clas, S.-D., Sanchez, R.I., and Nofsinger, R.Chemistry-enabled drug delivery (prodrugs): Recent progress and challengesDrug Discov. Today19(1),79-87(2014)
