Losartan
Cat. No.：YN321156
| 产品名称: | Losartan |
| CAS No.: | 114798-26-4 |
| Chemical Name: | 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol; 1-[1-[[2'-(2H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1H-imidazol-5-yl]methanol; 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]met |
| Synonyms: | 氯沙坦; DuP-753 |
| 分子量: | 422.91 |
| 分子式: | C₂₂H₂₃ClN₆O |
| SMILES: | OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Losartan 是血管紧张素II受体拮抗剂，与血管紧张素II竞争性结合AT1受体，IC50为20 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Chiu, T.A., et al.: J. Pharmacol. Exp. Ther., 252, 711 (1990)
McIntyre, M., et al.: Pharmacol. Ther., 74, 181 (1997)
Pitt, B., et al.: Lancet, 355, 1582 (2000)
