Irbesartan
Cat. No.：YN321424
CAS No. ：138402-11-6
| 产品名称: | Irbesartan |
| CAS No.: | 138402-11-6 |
| Chemical Name: | 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one |
| Synonyms: | 厄贝沙坦; SR-47436; BMS-186295 |
| 分子量: | 428.53 |
| 分子式: | C₂₅H₂₈N₆O |
| SMILES: | O=C1N(CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2)C(CCCC)=NC15CCCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Irbesartan是1型血管紧张素II（AT1）受体拮抗剂，IC50为1.3 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Burnier, M.Angiotensin II type 1 receptor blockersCirculation103(6),904-912(2001)
Gradman, A.H.AT1-receptor blockers: Differences that matterJ. Hum. Hypertens.16,S9-S16(2002)
Shimamura, T., Masui, M., Torii, M., et al.Hypotensive and prophylactic effects of angiotensin II subtype 1 receptor antagonist, irbesartan, in stroke-prone spontaneously hypertensive ratsClin. Exp. Hypertens.26(1),27-42(2004)
Candido, R., Allen, T.J., Lassila, M., et al.Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosisCirculation109(12),1536-1542(2004)
