Fimasartan
Cat. No.：YN321577
CAS No. ：247257-48-3
| 产品名称: | Fimasartan |
| CAS No.: | 247257-48-3 |
| Chemical Name: | 2-butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-5-pyrimidineethanethioamide |
| Synonyms: | 非马沙坦; BR-A-657 |
| 分子量: | 501.65 |
| 分子式: | C₂₇H₃₁N₇OS |
| SMILES: | O=C1N(C(CCCC)=NC(C)=C1CC(N(C)C)=S)CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fimasartan(BR-A-657) 是血管紧张素受体 AT1 非肽类拮抗剂，用于研究高血压和心力衰竭。 |
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Chi, Y.H., Lee, J.H., Kim, J.H., et al.Pharmacological characterization of BR-A-657, a highly potent nonpeptide angiotensin II receptor antagonistBiol. Pharm. Bull.36(7),1208-1215(2013)
Ryu, S., Shin, J.-S., Cho, Y.-W., et al.Fimasartan, anti-hypertension drug, suppressed inducible nitric oxide synthase expressions via nuclear factor-kappa B and activator protein-1 inactivationBiol. Pharm. Bull.36(3),467-474(2013)
