Angiotensin III, human, mouse
Cat. No.:YN321959
CAS No. :13602-53-4
产品名称: | Angiotensin III, human, mouse |
CAS No.: | 13602-53-4 |
Chemical Name: | 5-L-isoleucine-2-8-angiotensin II |
Synonyms: | 血管紧张素III,Angiotensin III, human, mouse(3TFA) |
分子量: | 931.09 |
分子式: | C₄₆H₆₆N₁₂O₉ |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Angiotensin III, human, mouse 是一种七肽,为血管紧张素 2 型受体 (AT2R) 激动剂,对 AT2R 和 AT1R 的IC50值分别为 0.648 nM 和 21.1 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Bosnyak, S., Jones, E.S., Christopoulos, A., et al.Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptorsClin. Sci. (Lond.)121(7),297-303(2011)
Wright, J.W., and Harding, J.W.Brain renin-angiotensin--a new look at an old systemProg. Neurobiol.95(1),49-67(2011)
Kemp, B.A., Bell, J.F., Rottkamp, D.M., et al.Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptorsHypertension60(2),387-395(2012)
Blair-West, J.R., Coghlan, J.P., Denton, D.A., et al.A dose-response comparison of the actions of angiotensin II and angiotensin III in sheepJ. Endocrinol.87(3),409-417(1980)
Gao, J., Marc, Y., Iturrioz, X., et al.A new strategy for treating hypertension by blocking the activity of the brain renin-angiotensin system with aminopeptidase A inhibitorsClin. Sci. (Lond.)127(3),135-148(2014)