Clioquinol
Cat. No.:YN250590
产品名称: | Clioquinol |
CAS No.: | 130-26-7 |
Chemical Name: | 5-chloro-7-iodo-8-quinolinol |
Synonyms: | Iodochlorhydroxyquin |
分子量: | 305.50 |
分子式: | C₉H₅ClINO |
SMILES: | ClC1=C(C=CC=N2)C2=C(O)C(I)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Clioquinol (Iodochlorhydroxyquin) 是一种局部抗真菌药,具有抗肿瘤活性。Clioquinol 作为口服抗菌剂,可用于腹泻和皮肤感染的研究。 |
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Ben Yaakov, D., Shadkchan, Y., Albert, N., et al.The quinoline bromoquinol exhibits broad-spectrum antifungal activity and induces oxidative stress and apoptosis in Aspergillus fumigatusJ. Antimicrob. Chemother.72(8),2263-2272(2017)
Finkelstein, D.I., Hare, D.J., Billings, J.L., et al.Clioquinol improves cognitive, motor function, and microanatomy of the α-Synuclein hA53T transgenic miceACS Chem. Neurosci.7(1),119-129(2016)
Lei, P., Ayton, S., Appukuttan, A.T., et al.Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouseNeurobiol. Dis.81,168-175(2015)