Ivermectin
Cat. No.：YN250632
| 产品名称: | Ivermectin |
| CAS No.: | 70288-86-7 |
| Chemical Name: | 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin; |
| Synonyms: | 伊维菌素; MK-933 |
| 分子量: | 875.09 |
| 分子式: | C₄₈H₇₄O₁₄ |
| SMILES: | CO[C@H]1C[C@H](O[C@H]2[C@H](C)O[C@@H](O[C@H](/C(C)=C/C[C@@H]3C[C@H]4C[C@@]5(O[C@]([H])(C(C)C)[C@@H](C)CC5)O3)[C@@H](C)/C=C/C=C6CO[C@@]7([H])[C@]\6(O)[C@H](C(O4)=O)C=C(C)[C@H]7O)C[C@@H]2OC)O[C@@H](C)[C@@H]1O.CO[C@H]8C[C@H](O[C@H]9[C@H](C)O[C@@H](O[C@H](/C( |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ivermectin (MK-933) 是一种广谱的抗寄生虫药物。Ivermectin (MK-933) 是一种特异性的Impα/β1 介导的核导入抑制剂，对 HIV-1 和登革热病毒都具有很强的抗病毒活性。Ivermectin (MK-933) 也是P2X4和 α7nAChRs的正异构效应物。Ivermectin 还可抑制牛疱疹病毒 1 (BoHV-1) 复制并抑制BoHV-1DNA 聚合酶的核输入。Ivermectin 是应用于抗SARS-CoV-2/COVID-19的候选药物。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Campbell, W.C., Fisher, M.H., Stapley, E.O., et al.Ivermectin: A potent new antiparasitic agentScience221(4613),823-828(1983)
