Rifampicin
Cat. No.：YN250975
| 产品名称: | Rifampicin |
| CAS No.: | 13292-46-1 |
| Chemical Name: | 3-[[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin |
| Synonyms: | 利福平; Rifampin; Rifamycin AMP |
| 分子量: | 822.94 |
| 分子式: | C₄₃H₅₈N₄O₁₂ |
| SMILES: | OC(C(/C=N/N1CCN(C)CC1)=C(NC(/C(C)=C\C=C\[C@@H]([C@@H]([C@@H](C)[C@H]2O)O)C)=O)C(O)=C3C(O)=C4C)=C3C5=C4O[C@](C)(O/C=C/[C@@H]([C@H]([C@@]([C@@H]2C)([H])OC(C)=O)C)OC)C5=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rifampicin是一种有效的广谱抗生素，可抵抗细菌病原体。Rifampicin 具有抗流感病毒活性。 |
| IC50和靶点: | |
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Wehrli, W.Rifampin: Mechanisms of action and resistanceRev. Infect. Dis.5(3),S407-S411(1983)
Jhamb, S.S., Goyal, A., and Singh, P.P.Determination of the activity of standard anti-tuberculosis drugs against intramacrophage Mycobacterium tuberculosis, in vitro: MGIT 960 as a viable alternative for BACTEC 460Braz. J. Infect. Dis.18(3),336-340(2014)
Arioli, V., Berti, M., Carniti, G., et al.Antibacterial activity of DL 473, a new semisynthetic rifamycin derivativeJ. Antibiot. (Tokyo)34(8),1026-1032(1981)
Gill, S.K., Xu, H., Kirchhoff, P.D., et al.Structure-based design of novel benzoxazinorifamycins with potent binding affinity to wild-type and rifampin-resistant mutant Mycobacterium tuberculosis RNA polymerasesJ. Med. Chem.55(8),3814-3826(2012)
