PSI-7976
Cat. No.：YN252001
| 产品名称: | PSI-7976 |
| CAS No.: | 1190308-01-0 |
| Chemical Name: | (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methy |
| Synonyms: | |
| 分子量: | 529.45 |
| 分子式: | C22H29FN3O9P |
| SMILES: | O=[P@](N[C@@H](C)C(OC(C)C)=O)(OC[C@@H]1[C@@H](O)[C@](F)(C)[C@H](N2C=CC(NC2=O)=O)O1)OC3=CC=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PSI-7976是PSI-7977(HY-15005)的同分异构体，能抑制HCV RNA复制，EC50为1.07uM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012)
Lam, A.M., et al.: J. Virol., 85, 12334 (2011)
Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)
