DDD85646
Cat. No.：YN252010
CAS No. ：1215010-55-1
| 产品名称: | DDD85646 |
| CAS No.: | 1215010-55-1 |
| Chemical Name: | 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide |
| Synonyms: | DDD85646 |
| 分子量: | 495.4 |
| 分子式: | C21H24Cl2N6O2S |
| SMILES: | ClC1=CC(C2=CC=NC(N3CCNCC3)=C2)=CC(Cl)=C1S(NC4=C(C)N(C)N=C4C)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | DDD85646 是一种有效的布氏锥虫 N-肉豆蔻酰转移酶 (NMT)抑制剂 (TbNMTIC50=2 nm；hNMTIC50< /sub>=4 纳米)。N-肉豆蔻酰转移酶 (NMT) 是人类非洲锥虫病的潜在活性分子靶点。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Frearson, J.A., Brand, S., McElroy, S.P., et al.N-myristoyltransferase inhibitors as new leads to treat sleeping sicknessNature464(7829),728-732(2010)
