GNF179
Cat. No.：YN252018
CAS No. ：1261114-01-5
| 产品名称: | GNF179 |
| CAS No.: | 1261114-01-5 |
| Chemical Name: | 2-Amino-1-[3-[(4-chlorophenyl)amino]-2-(4-fluorophenyl)-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin-7(8H)-yl]ethanone; GNF 179 |
| Synonyms: | |
| 分子量: | 427.9 |
| 分子式: | C22H23ClFN5O |
| SMILES: | CC1(C)C2=NC(C3=CC=C(F)C=C3)=C(NC4=CC=C(Cl)C=C4)N2CCN1C(CN)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GNF179 是一种优化的 8,8-dimethyl imidazolopiperazine 类似物，具有抗疟疾 (antimalarial) 活性，对多药耐药菌株 W2 的IC50为 4.8 nM。GNF179 具有口服活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Meister, S., ET al.: Science, 334, 1372 (2011)
