PF-04753299
Cat. No.：YN252022
| 产品名称: | PF-04753299 |
| CAS No.: | 1289620-49-0 |
| Chemical Name: | N-hydroxy-αR-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide |
| Synonyms: | PF-04753299 |
| 分子量: | 347.42968 |
| 分子式: | C18H21NO4S |
| SMILES: | ONC([C@@](S(C)(=O)=O)(C)CCC1=CC=C(C2=CC=CC=C2)C=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-04753299 是一种有效的、选择性的LpxC抑制剂。PF-04753299 对淋球菌具有杀菌作用，对大肠杆菌、铜绿假单胞菌和肺炎菌株的抑制的MIC90值分别为 2 μg/ml、4 μg/ml 和 16 μg/ml。PF-04753299 用于革兰氏阴性菌感染的研究。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Brown, M.F., Reilly, U., Abramite, J.A., et al.Potent inhibitors of LpxC for the treatment of Gram-negative infectionsJ. Med. Chem.55(2),914-923(2012)
