Abafungin
Cat. No.：YN252024
| 产品名称: | Abafungin |
| CAS No.: | 129639-79-8 |
| Chemical Name: | N-[4-[2-(2,4-dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine |
| Synonyms: | BAY-W-6341 |
| 分子量: | 378.49174 |
| 分子式: | C21H22N4OS |
| SMILES: | CC1=CC(C)=CC=C1OC2=C(C=CC=C2)C3=CSC(NC4=NCCCN4)=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Abafungin是一种抗真菌活性分子，可以抑制固醇侧链C-24位点的甲基转移，这种转移是由sterol-C-24-methyltransferase催化的。 |
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Borelli, C., Schaller, M., Niewerth, M., et al.Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungiChemotherapy54(4),245-259(2022)
