Samatasvir
Cat. No.：YN252026
CAS No. ：1312547-19-5
| 产品名称: | Samatasvir |
| CAS No.: | 1312547-19-5 |
| Chemical Name: | N-[(1R)-2-[(2S)-2-[5-[4-[6-[2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]-1H-benzimidazol-6-yl]thieno[3,2-b]thien-3-yl]phenyl]-1H-imidazol-2-yl]-1-pyrrolidinyl]-2-oxo-1-phenylethyl]-carbamic acid, methyl ester |
| Synonyms: | IDX719; IDX18719 |
| 分子量: | 885.06634 |
| 分子式: | C47H48N8O6S2 |
| SMILES: | O=C([C@H](C(C)C)NC(OC)=O)N1CCC[C@@]1([H])C(N2)=NC(C2=C3)=CC=C3C4=CSC5=C4SC=C5C6=CC=C(C7=CN=C([C@]8([H])CCCN8C([C@@H](C9=CC=CC=C9)NC(OC)=O)=O)N7)C=C6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Samatasvir (IDX71) 是一种有效的，具有口服活性的NS5AHCV复制抑制剂。Samatasvir 对感染性HCV和复制子有效且有选择性，在基因型 1至5 复制子中，EC50在 2 至 24 pM 的范围内。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bilello, J.P., Lallos, L.B., McCarville, J.F., et al.In vitro activity and resistance profile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virusAntimicrob. Agents Chemother.58(8),4431-4442(2014)
