Sofosbuvir impurity F
Cat. No.:YN252034
产品名称: | Sofosbuvir impurity F |
CAS No.: | 1337482-17-3 |
Chemical Name: | (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate |
Synonyms: | 索非布韦杂质 F |
分子量: | 798.69 |
分子式: | C34H45FN4O13P2 |
SMILES: | O=[P@@](N[C@@H](C)C(OC(C)C)=O)(OC[C@@H]1[C@@H](O[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)[C@](F)(C)[C@H](N3C(NC(C=C3)=O)=O)O1)OC4=CC=CC=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Sofosbuvir impurity F 是 Sofosbuvir 的非对映异构体,是 Sofosbuvir 的杂质。Sofosbuvir (PSI-7977) 是HCVRNA复制的抑制剂,表现出有效的抗丙型肝炎病毒活性。 |
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Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012)
Lam, A.M., et al.: J. Virol., 85, 12334 (2011)
Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)