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DL-Pyroglutamic acid

Cat. No.:YN252062

  • CAS No. :149-87-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: DL-Pyroglutamic acid
      CAS No.: 149-87-1
      Chemical Name: 5-oxo-proline
      Synonyms:
      分子量:129.11402
      分子式:C5H7NO3
      SMILES:O=C1CCC(C(O)=O)N1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: DL-Pyroglutamic acid 作为乙型肝炎表面灭活剂,除脊髓灰质炎病毒外,能够灭活痘苗病毒、单纯疱疹病毒和流感病毒。DL-Pyroglutamic acid 也是一种可能的氨基丁酸 (GABA) 转氨酶抑制剂,增加 GABA 含量并具有抗癫痫作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Meshram, A., Bhagyawant, S.S., and Srivastava, N.Characterization of pyrrolidine alkaloids of Epipremnum aureum for their antitermite activity against subterranean termites with SEM studiesProc. Natl. Acad. Sci. India Sect. B Biol. Sci.89(1),53-62(2019)

      Martini, N., Parente, J.E., Toledo, M.E., et al.Antidepressant and antinociceptive activities in animal models and in vitro assessment of the anti-thyroid activity of bis(DL-pyroglutamate)magnesium complexPharmacol. Rep.71(6),1273-1280(2019)

      Adamyan, N.H., Topchyan, H.V., Poghosyan, V.H., et al.Synthesis and antinociceptive activity of GABA and pyroglutamic acid short peptidesPharm. Chem. J.56,339–344(2022)

      Palekar, A.G., Tate, S.S., Sullivan, J.F., et al.Accumulation of 50oxo-L-proline and 5-oxo-D-proline in the blood plasma in end stage renal diseaseBiochem. Med.14(3),339-345(1975)

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