2'-C-Methyladenosine
Cat. No.：YN252067
CAS No. ：15397-12-3
| 产品名称: | 2'-C-Methyladenosine |
| CAS No.: | 15397-12-3 |
| Chemical Name: | 2'-C-methyl-adenosine |
| Synonyms: | 2'-C-甲基腺苷 |
| 分子量: | 281.3 |
| 分子式: | C11H15N5O4 |
| SMILES: | NC1=NC=NC2=C1N=CN2[C@H]3[C@@](O)(C)[C@H](O)[C@@H](CO)O3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2'-C-Methyladenosine 是丙型肝炎病毒(HCV)复制的抑制剂。2'-C-Methyladenosine 抑制HCV复制子和 NS5B 催化的 RNA 合成，IC50值分别为 0.3 μM 和 1.9 μM。2'-C-Methyladenosine 还有效抑制Leishmaniaguyanensis (Lgy)和Leishmaniabraziliensis中的 LRV1。 |
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Carroll, S.S., Tomassini, J.E., Bosserman, M., et al.Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogsJ. Biol. Chem.278(14),11979-11984(2003)
Robinson, J.I., and Beverley, S.M.Concentration of 2'C-methyladenosine triphosphate by Leishmania guyanensis enables specific inhibition of Leishmania RNA virus 1 by its RNA polymeraseJ. Biol. Chem.,(2018)
