HBV-IN-22
Cat. No.:YN252074
产品名称: | HBV-IN-22 |
CAS No.: | 1578153-27-1 |
Chemical Name: | |
Synonyms: | RO 6889678 |
分子量: | 494.92 |
分子式: | C21H20ClFN4O5S |
SMILES: | ClC1=CC(F)=CC=C1C1N=C(C2SC=CN=2)NC(CN2CCOCC2C(O)=O)=C1C(OC)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | RO6889678 是一种高效的HBV衣壳结构抑制剂,具有复杂的吸收、分布、代谢和排泄 (ADME) 特征。RO6889678 是人肝细胞中 CYP3A4 和共调节蛋白的有效诱导剂。RO6889678 通过 CYP3A4 介导的氧化和 UDP-葡萄糖醛酸基转移酶 UGT1A3 和 UGT1A1 介导的直接葡萄糖醛酸化作用进行代谢。 |
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