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Abametapir

Cat. No.:YN252085

  • CAS No. :1762-34-1

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    • 参考文献
    • 产品名称: Abametapir
      CAS No.: 1762-34-1
      Chemical Name: 5,5′-dimethyl-2,2′-bipyridine
      Synonyms:5,5'-Dimethyl-2,2'-bipyridine;5,5'-Dimethyl-2,2'-bipyridyl;5,5'-DIMETHYL-2,2'-DIPYRIDYL;5,5′-Dimethyl-2,2′-bipyridine;5-methyl-2-(5-methylpyridin-2-yl)pyridine;2,2'-BIPYRIDINE,5,5'-DIMETHYL;5,5'-dimethyl-2,2'-bipy;5,5'-dimethyl-2,2'-bispyridine;5,5'-dimet
      分子量:184.23716
      分子式:C12H12N2
      SMILES:CC1=CC=C(C2=CC=C(C)C=N2)N=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Abametapir 是一种金属蛋白酶 (MMP) 抑制剂,能够靶向对卵孵化和虱子发育至关重要的金属蛋白酶。Abametapir 对头虱和体虱的孵化均有抑制作用。
      IC50和靶点:
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    • Zhou, M.-X., Ren, N., Zhang, J.-J., et al.Synthesis, crystal structure, thermal, luminescent property and antibacterial activity of lanthanide ternary complexes with p-chlorobenzoic acid and 5,5′-dimethyl-2,2′-bipyridineJ. Mol. Struct.1200,127049(2020)

      Xing, B., Yu, C.-W., Ho, P.-L., et al.Multivalent antibiotics via metal complexes: Potent divalent vancomycins against vancomycin-resistant enterococciJ. Med. Chem.46(23),4904-4909(2003)

      Bowles, V.M., Yoon, K.S., Barker, S.C., et al.Ovicidal efficacy of abametapir against eggs of human head and body lice (Anoplura: Pediculidae)J. Med. Entomol.54(1),167-172(2017)

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