Baloxavir
Cat. No.：YN252098
CAS No. ：1985605-59-1
| 产品名称: | Baloxavir |
| CAS No.: | 1985605-59-1 |
| Chemical Name: | (12aR)-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-3,4,12,12a-tetrahydro-7-hydroxy-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione |
| Synonyms: | Baloxavir acid; S-033447 |
| 分子量: | 483.4882864 |
| 分子式: | C24H19F2N3O4S |
| SMILES: | O=C1C(N(C=C2)N([C@@H]3C4=CC=CC=C4SCC5=C(F)C(F)=CC=C53)[C@@]6([H])N1CCOC6)=C(O)C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Baloxavir (Baloxavir acid)，衍生自前体 Baloxavir marboxil，是甲型和乙型流感病毒聚合酶 PA 亚基内的一种首创，有效且选择性的帽依赖性核酸内切酶 (CEN) 抑制剂。Baloxavir 抑制病毒 RNA 的转录和复制，并具有强大的抗病毒活性。 |
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Noshi, T., Kitano, M., Taniguchi, K., et al.In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunitAntiviral Res.160,109-117(2017)
