HCV-IN-31
Cat. No.:YN252100
CAS No. :1998705-62-6
产品名称: | HCV-IN-31 |
CAS No.: | 1998705-62-6 |
Chemical Name: | (2′R)-2-amino-2′-deoxy-2′-fluoro-N,2′-dimethyl-adenosine |
Synonyms: | |
分子量: | 312.3004232 |
分子式: | C12H17FN6O3 |
SMILES: | C[C@@]1([C@](O[C@@H]([C@H]1O)CO)([H])N2C3=NC(N)=NC(NC)=C3N=C2)F |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | HCV-IN-31 (compound 4) 是HCV的抑制剂,其抑制HCV复制子的EC50/EC95值为15.7 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Good, S.S., Moussa, A., Zhou, X.-J., et al.Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virusPLoS One15(1),e0227104(2020)
Sommadossi, J.-P., and Moussa, A.Beta-D-2'-deoxy-2'-alpha-fluoro-2'-beta-C-substituted-2-modified-N6-substituted purine nucleotides for HCV treatment,(2016)