Bemnifosbuvir
Cat. No.：YN252101
CAS No. ：1998705-64-8
| 产品名称: | Bemnifosbuvir |
| CAS No.: | 1998705-64-8 |
| Chemical Name: | N-[[P(S),2′R]-2-amino-2′-deoxy-2′-fluoro-N,2′-dimethyl-P-phenyl-5′-adenylyl]-L-alanine, 1-methylethyl ester |
| Synonyms: | AT-511 |
| 分子量: | 581.5339642 |
| 分子式: | C24H33FN7O7P |
| SMILES: | CC(C)OC([C@H](C)N[P@](OC[C@@H]1[C@@H](O)[C@](F)(C)[C@]([H])(N2C=NC3=C(NC)N=C(N)N=C32)O1)(OC4=CC=CC=C4)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bemnifosbuvir 是一种有效的具有口服活性的HCV病毒复制抑制剂。Bemnifosbuvir 有效抑制SARS-CoV-2 (COVID-19)感染 (EC90=0.47 μM)。Bemnifosbuvir 具有全基因型抗病毒活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Good, S.S., Westover, J., Jung, K.H., et al.AT-527, a double prodrug of a guanosine nucleotide analog, is a potent inhibitor of SARS-CoV-2 in vitro and a promising oral antiviral for treatment of COVID-19Antimicrob. Agents Chemother.65(4),e02479-02420(2021)
