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Reuterin

Cat. No.:YN252111

  • CAS No. :2134-29-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Reuterin
      CAS No.: 2134-29-4
      Chemical Name: 3-hydroxy-propanal
      Synonyms:3-Hydroxypropionaldehyde; 3-Hydroxypropanal
      分子量:74.07854
      分子式:C3H6O2
      SMILES:O=CCCO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Reuterin 是一种广谱抗菌剂 (antimicrobial),由Lactobacillus reuteri在甘油厌氧代谢过程中产生。Reuterin 是一种对革兰氏阳性菌和革兰氏阴性菌,以及酵母菌、霉菌和原生动物有效的抗菌剂。Reuterin 对广泛的人和禽肉弯曲杆菌属分离物具有很强的抗菌活性。
      IC50和靶点:
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    • Talarico, T.L., Casas, I.A., Chung, T.C., et al.Production and isolation of reuterin, a growth inhibitor produced by Lactobacillus reuteriAntimicrob. Agents Chemother.32(12),1854-1858(1988)

      Schaefer, L., Auchtung, T.A., Hermans, K.E., et al.The antimicrobial compound reuterin (3-hydroxypropionaldehyde) induces oxidative stress via interaction with thiol groupsMicrobiology (Reading)156(Pt 6),1589-1599(2010)

      Cleusix, V., Lacroix, C., Vollenweider, S., et al.Inhibitory activity spectrum of reuterin produced by Lactobacillus reuteri against intestinal bacteriaBMC Microbiol.7,101(2007)

      Engevik, M.A., Danhof, H.A., Shrestha, R., et al.Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generationGut Microbes12(1),1788898(2020)

      Castellani, C., Obermüller, B., Kienesberger, B., et al.Production, storage stability, and susceptibility testing of reuterin and its impact on the murine fecal microbiome and volatile organic compound profileFront. Microbiol.12,699858(2021)

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