Reverse transcriptase-IN-1
Cat. No.：YN252128
CAS No. ：2380001-43-2
| 产品名称: | Reverse transcriptase-IN-1 |
| CAS No.: | 2380001-43-2 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 447.45 |
| 分子式: | C25H17N7O2 |
| SMILES: | N#CC1=CC=C(NC2=NC(NC3=C([N+]([O-])=O)C=C(/C=C/C#N)C=C3C)=C4C=CC=CC4=N2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Reverse transcriptase-IN-1 (Compound 12z)，二芳基苯并嘧啶 (DABP) 类似物， 是一种有效的，具有口服活性的HIV-1非核苷逆转录酶抑制剂。Reverse transcriptase-IN-1 具有抗病毒活性，对HIV-1IIIB，E138K和K103N突变体的EC50值分别为 3.4 nM，4.3 nM 和 3.6 nM，而且对HIV-1逆转录酶的IC50值为 13.7 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
