BSH-IN-1
Cat. No.：YN252136
CAS No. ：2553217-91-5
| 产品名称: | BSH-IN-1 |
| CAS No.: | 2553217-91-5 |
| Chemical Name: | (R)-5-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-fluorohexan-2-one |
| Synonyms: | |
| 分子量: | 408.5896432 |
| 分子式: | C25H41FO3 |
| SMILES: | FCC(CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BSH-IN-1 是一种重组的肠道细菌胆汁盐水解酶 (BSHs) 的有效和共价抑制剂，对B. longumBSH (革兰氏阳性) 和B. thetaBSH (革兰氏阴性菌) 的IC50分别为 108 和 427 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Adhikari, A.A., Seegar, T.C., Ficarro, S.B., et al.Development of a covalent inhibitor of gut bacterial bile salt hydrolasesNat. Chem. Biol.16(3),318-326(2020)
