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Gusperimus trihydrochloride

Cat. No.:YN252146

  • CAS No. :27267-70-5

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    • 参考文献
    • 产品名称: Gusperimus trihydrochloride
      CAS No.: 27267-70-5
      Chemical Name: (2S)-4,4',9,9'-tetrahydro-8',10-dihydroxy-5',7'-dimethoxy-4',9,9'-trioxo-spiro[benzo[1,2-b:5,4-c']dipyran-2(3H),2'(3'H)-naphtho[2,3-b]furan]-7-carboxylic acid, methyl ester
      Synonyms:
      分子量:536.4405
      分子式:C27H20O12
      SMILES:O=C(OC)C(O1)=CC(C=C(CC[C@@]2(OC(C(C(C(O)=C(OC)C=C3OC)=C3C4=O)=O)=C4C2)O5)C5=C6O)=C6C1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: β-Rubromycin 是人类免疫缺陷病毒-1 (HIV-1) RNA 导向的 DNA 聚合酶的有效和选择性抑制剂 (逆转录酶)。β-红霉素是一类醌类抗菌剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Ueno, T., Takahashi, H., Oda, M., et al.Inhibition of human telomerase by rubromycins: Implication of spiroketal system of the compounds as an active moietyBiochemistry39(20),5995-6002(2000)

      Puder, C., Loya, S., Hizi, A., et al.Structural and biosynthetic investigations of the rubromycinsEur. J. Org. Chem.2000(5),729-735(2000)

      Goldman, M.E., Salituro, G.S., Bowen, J.A., et al.Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: Competitive interaction at the template.primer siteMol. Pharmacol.38(1),20-25(1990)

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