Ensitrelvir fumarate
Cat. No.：YN252147
CAS No. ：2757470-18-9
| 产品名称: | Ensitrelvir fumarate |
| CAS No.: | 2757470-18-9 |
| Chemical Name: | (6E)-6-[(6-chloro-2-methyl-2H-indazol-5-yl)imino]dihydro-3-[(1-methyl-1H-1,2,4-triazol-3-yl)methyl]-1-[(2,4,5-trifluorophenyl)methyl]-1,3,5-triazine-2,4(1H,3H)-dione, (2E)-2-butenedioate |
| Synonyms: | S-217622 fumarate |
| 分子量: | 647.9499096 |
| 分子式: | C22H17ClF3N9O2 • C4H4O4 |
| SMILES: | O=C(N/1CC2=CC(F)=C(C=C2F)F)N(C(NC1=N/C3=CC4=CN(N=C4C=C3Cl)C)=O)CC5=NN(C=N5)C.O=C(/C=C/C(O)=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ensitrelvir (S-217622) fumarate 是第一个具有口服活性的，非共价的、非肽SARS-CoV-2 3CL蛋白酶抑制剂 (IC50=13 nM)。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Unoh, Y., Uehara, S., Nakahara, K., et al.Discovery of S-217622, a noncovalent oral SARS-CoV-2 3CL protease inhibitor clinical candidate for treating COVID-19J. Med. Chem.65(9),6499-6512(2022)
