Omadacycline
Cat. No.：YN252167
| 产品名称: | Omadacycline |
| CAS No.: | 389139-89-3 |
| Chemical Name: | 4,7-bis(dimethylamino)-9-[[(2,2-dimethylpropyl)amino]methyl]-1,4S,4aS,5,5aR,6,11,12aS-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide |
| Synonyms: | PTK 0796; Amadacycline |
| 分子量: | 556.7 |
| 分子式: | C29H40N4O7 |
| SMILES: | CN(C)[C@H](C(O)=C1C(N)=O)[C@@]2([H])[C@@](C(O)=C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C4)=O)[C@]4([H])C2)(O)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Omadacycline (PTK 0796) tosylate，首创的具有口服活性的氨基甲基环素抗菌剂，是一种四环素类抗生素。Omadacycline tosylate 通过与 30S 核糖体亚基结合来抑制细菌蛋白质的合成。Omadacycline tosylate 对多种细菌表现出活性，包括好氧和厌氧革兰氏阳性细菌和革兰氏阴性细菌，非典型病原体。Omadacycline tosylate 可用于研究急性细菌性皮肤和皮肤结构感染，感染性肺炎和尿路感染。 |
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Macone, A.B., Caruso, B.K., Leahy, R.G., et al.In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcyclineAntimicrob. Agents Chemother.58(2),1127-1135(2014)
