Antibacterial agent 104
Cat. No.:YN252168
产品名称: | Antibacterial agent 104 |
CAS No.: | 39277-41-3 |
Chemical Name: | (1R,7'aR,11'aR,12'R)-rel-(-)-7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide |
Synonyms: | Viridicatumtoxin; SC 28762; SC-28762; SC28762; Viriditoxin; |
分子量: | 565.56788 |
分子式: | C30H31NO10 |
SMILES: | O[C@@H]1[C@]2(O)[C@](C(C(C(N)=O)=C(O)C2)=O)(O)C(C3=C(O)C4=C(O)C=C(OC)C5=C4C(C[C@]56C(C)(C)CCC=C6C)=C31)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Viridicatumtoxin 是从绿色青霉菌中提取的一种新型霉菌毒素,在大鼠体内的LD50为 122.4 mg/kg。 |
IC50和靶点: | |
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Hutchinson, R.D., Steyn, P.S., and Van Rensburg, S.J.Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum WestlingToxicol. Appl. Pharmacol.24(30),507-509(1973)
Bladt, T.T., Dürr, C., Knudsen, P.B., et al.Bio-activity and dereplication-based discovery of ophiobolins and other fungal secondary metabolites targeting leukemia cellsMolecules18(12),14629-14650(2013)
Inokoshi, J., Nakamura, Y., Komada, S., et al.Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal moleculesJ. Antibiot. (Tokyo)69(11),798-805(2016)
Bendele, A.M., Carlton, W.W., Nelson, G.E., et al.Viridicatumtoxin mycotoxicosis in mice and ratsToxicol. Lett.22(3),287-291(1984)