(R)-4-Methoxydalbergione
Cat. No.：YN252170
| 产品名称: | (R)-4-Methoxydalbergione |
| CAS No.: | 4085-31-8 |
| Chemical Name: | 4,4'-(1,3-propanediyldi-4,1-piperazinediyl)bis[7-chloro-quinoline |
| Synonyms: | |
| 分子量: | 535.5 |
| 分子式: | C29H32Cl2N6 |
| SMILES: | ClC1=CC2=C(C=C1)C(N3CCN(CC3)CCCN4CCN(CC4)C5=C6C=CC(Cl)=CC6=NC=C5)=CC=N2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Piperaquine 是一种双喹啉抗疟药 (antimalarial)，可以与青蒿素联用于抗疟研究。 |
| IC50和靶点: | |
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Akoachere, M., Buchholz, K., Fischer, E., et al.In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisininsAntimicrob. Agents Chemother.49(11),4592-4597(2005)
Askling, H.H., Bruneel, F., Burchard, G., et al.Management of imported malaria in EuropeMalar. J.11,(2012)
Henrich, P.P., O'Brien, C., Sáenz, F.E., et al.Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent modelAntimicrob. Agents Chemother.58(1),183-195(2014)
Pascual, A., Parola, P., Benoit-Vical, F., et al.Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparumMalar. J.11,(2012)
