Vapendavir
Cat. No.：YN252175
| 产品名称: | Vapendavir |
| CAS No.: | 439085-51-5 |
| Chemical Name: | 3-ethoxy-6-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-1,2-benzisoxazole |
| Synonyms: | BTA798 |
| 分子量: | 382.4563 |
| 分子式: | C21H26N4O3 |
| SMILES: | CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C21 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vapendavir (BTA798) 是一种有效的肠病毒衣壳粘合剂 (CB)。Vapendavir (BTA798) 可抑制EV71的复制，对 EV71 不同毒株的EC50值为 0.5-1.4 μM。 |
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Feil, S.C., Hamilton, S., Krippner, G.Y., et al.An orally available 3-ethoxybenzisoxazole capsid binder with clinical activity against human rhinovirusACS Med. Chem. Lett.3(4),303-307(2012)
Tijsma, A., Franco, D., Tucker, S., et al.The capsid binder vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replicationAntimicrob. Agents Chemother.58(11),6990-6992(2014)
