Larixyl acetate
Cat. No.：YN252178
CAS No. ：4608-49-5
| 产品名称: | Larixyl acetate |
| CAS No.: | 4608-49-5 |
| Chemical Name: | (αS,1S,4S,4aS,8aR)-4-(acetyloxy)-α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol |
| Synonyms: | Larix-6-yl monoacetate |
| 分子量: | 348.51944 |
| 分子式: | C22H36O3 |
| SMILES: | C[C@]12[C@@](C(C)(CCC2)C)([H])[C@H](CC([C@@H]1CC[C@](C)(O)C=C)=C)OC(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Larixyl acetate 是一种有效的、选择性的TRPC6抑制剂，对hTRPC6-YFP和hTRPC3-YFP的IC50分别为 0.58 μM 和 6.83 μM。Larixyl acetate 预防HPV，对创伤性脑损伤引起的全身内皮功能障碍有效。 |
| IC50和靶点: | [{name:"hTRPC6:0.58 μM (IC50)"},{name: "hTRPC3:6.83 μM (IC50)"}] |
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| Solvent & Solubility: |
Urban, N., Wang, L., Kwiek, S., et al.Identification and validation of larixyl acetate as a potent TRPC6 inhibitorMol. Pharmacol.89(1),197-213(2016)
Wang, J., Zhao, M., Jia, P., et al.The analgesic action of larixyl acetate, a potent TRPC6 inhibitor, in rat neuropathic pain model induced by spared nerve injuryJ. Neuroinflammation17(1),118(2020)
