Brassicasterol
Cat. No.：YN252179
| 产品名称: | Brassicasterol |
| CAS No.: | 474-67-9 |
| Chemical Name: | ergosta-5,22E-dien-3β-ol |
| Synonyms: | 油菜甾醇 |
| 分子量: | 398.7 |
| 分子式: | C28H46O |
| SMILES: | CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)C3=CC[C@@]21C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Brassicasterol 是 Ergosterol 的一种代谢物，通过雄激素信号传导抑制膀胱癌的发生。Brassicasterol 对HSV-1(IC50=1.2 µM) 和 结核分枝杆菌及心血管保护作用。 Brassicasterol 通过双重靶向AKT和雄激素受体信号通路在前列腺癌中发挥抗癌作用。 |
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Fernández, C., Suárez, Y., Ferruelo, A.J., et al.Inhibition of cholesterol biosynthesis by Δ22-unsaturated phytosterols via competitive inhibition of sterol Δ24-reductase in mammalian cellsBiochem. J.366(Pt 1),109-119(2002)
Li, H., Zhao, X., Deng, X., et al.Insights into structure and activity of natural compound inhibitors of pneumolysinSci. Rep.7:42015,(2017)
