Artelinic acid
Cat. No.：YN252197
| 产品名称: | Artelinic acid |
| CAS No.: | 546-06-5 |
| Chemical Name: | N,N-dimethyl-con-5-enin-3β-amine |
| Synonyms: | Conessine; Conessinum; Konessin; Neriine; Roquessine; Wrightine; |
| 分子量: | 356.6 |
| 分子式: | C24H40N2 |
| SMILES: | C[C@H]1[C@@]2([H])CC[C@@]3([H])[C@]4([H])CC=C5C[C@@H](N(C)C)CC[C@]5(C)[C@@]4([H])CC[C@@]32CN1C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Conessine 是一种甾体生物碱，是一种有效的选择性组胺H3 受体拮抗剂，Ki分别为 5.4、6.0、5.7 和 25 nM 分别为人、狗、豚鼠和大鼠 H3受体。具有抗疟活性。 |
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Siddiqui, B.S., Ali, S.T., Rizwani, G.H., et al.Antimicrobial activity of the methanolic bark extract of Holarrhena pubescens (Buch. Ham), its fractions and the pure compound conessineNat. Prod. Res.26(11),987-992(2012)
Jayaswal, S.B.Amoebicidal activity of steroidal alkaloids of Wrightia tomentosa in vitroIndian J. Pharm.38(4),112-113(1976)
Dua, V.K., Verma, G., Singh, B., et al.Anti-malarial property of steroidal alkaloid conessine isolated from the bark of Holarrhena antidysentericaMalar. J.12,194(2013)
Shen, L., Niu, J., Wang, C., et al.High-throughput screening and identification of potent broad-spectrum inhibitors of coronavirusesJ. Virol.93(12),e00023-00019(2019)
Zhao, C., Sun, M., Bennani, Y.L., et al.The alkaloid conessine and analogues as potent histamine H3 receptor antagonistsJ. Med. Chem.51(17),5423-5430(2008)
